Wednesday, March 7, 2007

Why Bristol And Sanofi Shouldn't Merge

Pharmaceutical investors are enthused about the merger rumor du jour: the potential acquisition of New York drug maker Bristol-Myers Squibb by Paris-based Sanofi-Aventis. A French newsletter reported that the companies are in talks, while Bristol may have even hired bankers to scope out potential deals. Bristol-Myers shares have jumped nearly 10%.

In the long term, though, such a deal is probably a bad idea, one of those short-term fixes that has left drug companies scrambling to reinvigorate their research labs as fewer and fewer medicines actually make it to patients. It would be best for long-term investors and the drug industry if Bristol (nyse: BMY - news - people ) doesn't sell out.

Bristol and Sanofi chose not to comment for this story.

If I Ran Pfizer

The industry is at a crossroads, and all eyes are on the world's largest drug maker. When Pfizer leads, others follow. So we asked: If you had that sort of influence, how would you steer Big Pharma?

By: Beth Herskovits

When Pfizer CEO Jeffrey Kindler took the podium in January and announced that the struggling company would scale back and restructure its operations, he did more than just signal the end of an era. He proved that to turn around Pfizer—and in a way, the industry at large—companies need to hack away the parts that just aren't working anymore.

Certainly, the reorganization plan of the world's largest drug company is ambitious. It involves streamlining operations under five newly created business umbrellas, ramping up communications with payers and patients, ending smothering sales tactics with physicians, and cutting the fat out of middle management. In every sense, it was swift and unforgiving—but observers were unimpressed.

"It's not even close to revolutionary; I wouldn't even say it's evolutionary. It's just stand-pat," said Bill Trombetta, professor of pharmaceutical marketing at St. Joseph's University in Philadelphia, who noted that GlaxoSmithKline and Merck have already undertaken similar strategies. "They're not doing anything that's different from what any company would do when its back is against the wall."

The moves were all practical. Unable to build a beanstalk from its magic bean torcetrapib, Pfizer had no choice but to scale down its infrastructure. But observers didn't believe that Pfizer's plan got at the heart of the industry's troubles: the costly and time-intensive R&D process, higher hurdles at FDA, ever-present risk of unforeseen adverse events, and the ticking clock on blockbuster patents.

Trombetta and others talk about the need for drug companies to think beyond their role as drug suppliers and become companies that offer a strategic advantage to their customers. They're certainly capable of doing so. After all, it was Pfizer, Trombetta noted, that worked with Florida's Medicaid program in 2004 to fund health education, triage services, bloodpressure cuffs, scales, and other personal health aids for people who couldn't otherwise afford them.

But the program wasn't institutionalized. "The drug industry is there to sell products—it hasn't been there as a source of strategic advantage," Trombetta said.

"The ramifications are all the way up the chain: from drug discovery to what business pharma companies are in. Are they in the drug business or the solution business?" said Steve Wunker, a partner at consulting firm Innosight. "That will be the hardest challenge for pharma to address. They're very good at innovation—in the sense that they're good at finding new molecules—but they're very bad at innovating what they do."

Mighty Pfizer sets the tone for the rest of pharma. But now, when all eyes were on the industry's role model, some observers believed company executives dropped the ball. They talked about innovating new products, but they didn't talk about innovating what they do.

So we asked observers, critics and supporters, to fill in the missing pieces. If they ran Pfizer—or more specifically, a Big Pharma company that wielded a similar position of influence—what model would they create? How would they tackle the issues facing the industry?

Here's what they had to say.

Bristol, Boehringer Sales Teams Rank 1st

Taken from Forbes:

Bristol-Myers Squibb Co. and Boehringer Ingelheim Corp. ranked best in a new survey that ranks the effectiveness of the drug industry's sales forces set to be released Tuesday.

Bristol-Myers has the most effective team for targeting specialists while Boehringer's representatives were rated best at reaching primary care doctors, according to a survey of more than 20,000 physicians conducted by TargetRx Inc., a consulting company specializing in pharmaceutical sales and marketing. The survey covered a total of 210 brands but doctors were only asked about products that had been marketed to them.

The size and expense of drug companies' sales forces has increasingly become an issue as numerous drug makers seek to cut costs as many struggle with patent expirations and consumers' resistance to pricey medicines. Last year, Pfizer Inc. announced it was cutting 20 percent of its U.S. sales force while last week Abbott Laboratories said it was laying off several hundred representatives as it absorbs its purchase of Kos Pharmaceuticals Inc.

An average sales person costs a pharmaceutical company about $200,000 including salary and benefits such as a car, said Mike Luby, president and CEO of TargetRx. He said that the challenging business environment means it is imperative for drug makers' sales forces are as effective as possible.

Luby said the survey asked doctors about numerous issues including the quality of the marketing materials, the representative's knowledge of the product, disease and appropriate patient population and whether the sales person's pitch was balanced and efficient.

Pfizer, the world's largest drug company which is widely considered among the best marketers in the business, ranked 12th among primary care doctors and eighth among specialists. In a statement, Pfizer said it had fared better in other surveys and that overall its sales force has consistently held high rankings from physicians in the areas of performance, professionalism and customer focus.

Forest Pharmaceuticals Inc., a subsidiary of Forest Laboratories Inc., ranked last of the 16 companies rated by primary care doctors while Merck & Co. was in the basement of the 18 drug makers measured by specialists.

In a statement, Tony Hooper, Bristol-Myers' President of U.S. Pharmaceuticals, said that the company works closely with physicians to ensure that they have the information needed to make informed decisions for patients and that it was constantly measuring, evaluating and correcting its sales approach.

Boehringer spokesman Mark Vincent said the company strives to hire high-quality individuals and arm them with good information to help physicians. A core component of the strategy is to ensure sales people understand the realities of physicians' life such as their time constraints and contracts with numerous managed care companies, so the representatives can be as sensitive and useful as possible.

Merck said in a statement said that it introduced five medicines and vaccines last year and that "the strong uptake of these new products is a stronger measure than any survey.

Forest Labs declined comment while Boehringer, a privately held German company, didn't have an immediate comment.